Published August 1985
by Pergamon Pr .
Written in English
|The Physical Object|
|Number of Pages||180|
The history and present state of routine irritation testing The skin and mucous membranes of the eyes or the mouth are often subject to attack from the environment, whether from the use of dermatological and ophthalmological preparations and cosmetic and toiletry products or by accidental exposure to household products or industrial by: A Strategy for Skin Irritation Testing. Book. Full-text available These products are intended to be worn for prolonged periods of time on body sites that include the mucous membrane and. Despite the widespread recognition that mucosal irritation is a cardinal feature of "sick-building syndrome," few data exist on the cause, natural history, or pathophysiology of upper respiratory. methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes JOHN H. DRAIZE, GEOFFREY WOODARD and HERBERT O. CALVERY Journal of Pharmacology and Experimental Therapeutics Cited by:
Despite the widespread recognition that mucosal irritation is a cardinal feature of "sick-building syndrome," few data exist on the cause, natural history, or pathophysiology of upper respiratory mucous membrane irritation. The baseline prevalence of nasal symptoms among building occupants is often 20%, but in some studies it is as high as 50 Cited by: Start studying chapter 9 drugs that affect the skin and mucous membranes. Learn vocabulary, terms, and more with flashcards, games, and other study tools. The above findings, as well as the generally recognized relationship between the effects of chemicals on skin and mucous membranes, support the IRLG and OECD guidelines provision that substances found to be severely irritating in dermal irritation tests are assumed to be ocular irritants and, therefore, need not be tested in the eye. Learn skin and mucous membranes with free interactive flashcards. Choose from different sets of skin and mucous membranes flashcards on Quizlet.
Mucous membrane pemphigoid is an autoimmune blistering disease, which basically means that an individual's immune systems starts reacting against his or her own tissue. In this particular instance autoantibodies react with proteins found in mucous membranes and skin tissue resulting in blistering lesions. The binding site appears to be within. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes () by John H Draize, Geoffrey Woodard, Herbert Venue. to arise from exposure of the eyes and associated mucous membranes to the test substance. (2) Data on primary eye irritation are required by 40 CFR to support the registration of each manufacturing-use product and end-use product. (See § to determine whether these data must be submittedFile Size: 41KB. may cause skin irritation and allergic reactions. Moisturizers increase the hygroscopic properties of the skin; however, high concentration of these substances may cause irritation and exfoliation. Skin lightening/depigmenting agents, such as hydroquinone How to cite this article: Nigam PK. Adverse reactions to cosmetics and methods of testing.